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CAS 14113-05-4 10-HAD 10-Hydroxydec-2-Enoic Acid
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xM. F. | C10H18O3 | M. W. | 186.25 |
---|---|---|---|
Content | 99.0% | Appearance | Light Yellow Powder |
CAS | 14113-05-4 | Application | Food Nutritional Supplement |
Highlight | CAS 14113-05-4 10-HAD,C10H18O3 CAS 14113-05-4,10-HAD Food Nutritional Supplement |
10-HAD 10-hydroxydec-2-enoic acid CAS 14113-05-4 Food Nutritional Supplement
Specification
CAS | 14113-05-4 |
Purity | 99.0% |
MF | C10H18O3 |
MW | 186.25 |
Appearance | light yellow solid |
Application | Food Nutritional Supplement |
Description
10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.
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