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CAS 14113-05-4 10-HAD 10-Hydroxydec-2-Enoic Acid
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|M. F.||C10H18O3||M. W.||186.25|
|Content||99.0%||Appearance||Light Yellow Powder|
|CAS||14113-05-4||Application||Food Nutritional Supplement|
CAS 14113-05-4 10-HAD,
C10H18O3 CAS 14113-05-4,
10-HAD Food Nutritional Supplement
10-HAD 10-hydroxydec-2-enoic acid CAS 14113-05-4 Food Nutritional Supplement
|Appearance||light yellow solid|
|Application||Food Nutritional Supplement|
10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.
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