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NMN β-Nicotinamide Mononucleotide CAS 1094-61-7 Food Nutritional Supplement
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xM. F. | C11H15N2O8P | M. W. | 334.22 |
---|---|---|---|
Content | 99.0% | Appearance | White Powder |
CAS | 1094-61-7 | Application | Food Nutritional Supplement |
High Light | NMN Food Nutritional Supplement,1094-61-7 Food Nutritional Supplement,COA β Nicotinamide Mononucleotide |
NMN β-Nicotinamide Mononucleotide CAS 1094-61-7 Food Nutritional Supplement
Specification
CAS | 1094-61-7 |
Purity | 99.0% |
MF | C11H15N2O8P |
MW | 334.22 |
Appearance | White powder |
Application | Food Nutritional Supplement |
Description
Nicotinamide mononucleotide (NMN), a product of the NAMPT reaction and a key NAD+ intermediate, ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. NMN also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. NMN is used for studying binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.
β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.
β-Nicotinamide mononucleotide is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate β-NMN, which is subsequently converted to NAD+ by β-NMN adenyltransferase.At 50-100 μM, β-NMN has been used to enhance NAD biosynthesis and glucose-stimulated insulin secretion in a Nampt+/- mouse model of metabolic disease, demonstrating a role for Nampt in β cell function.Furthermore, at 500 mg/kg/day, it has been shown to ameliorate glucose intolerance in high-fat diet-induced type 2 diabetes mice by restoring NAD+ levels.
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FAQ
Q1: What is your regular lead time for sample and official order?
A1: Sample lead time 5-7 days. Official order lead time 14-21 days.
Q2: What is your MOQ?
A2: MOQ usually is 1kg.
Q3: How you control product quality?
A3: From raw material inspection, dupro inspection to final product inspection are executed strictly.
Q4: What is your warranty policy?
A4: We will send you a new batch if there is any quality issue during warranty time
Q5: Do you refund if customer receive defective product and do not accept replacement?
A5: Yes
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